Author

A. Trusina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Igbaria· 1 shared A. V. Nielsen· 1 shared F. R. Papa· 1 shared F. Tilahun· 1 shared J. M. Brickman· 1 shared J. R. Johnson· 1 shared J. S. Weissman· 1 shared K. Sneppen· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Igbaria

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Author profile →

4 papers

Recent·Most cited

Tipping-point transition from transient to persistent inflammation in pancreatic islets

T. H. Hansen, P. Y. Nielsen, M. H. Jensen, T. Mandrup-Poulsen, A. Trusina

This paper uses a computational model to show that pancreatic islets can switch between transient and persistent inflammation modes based on feedback loops and islet size.

npj Systems Biology and Applications · Sep 12, 2024Peer-reviewedBiophysics

A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation

T. E. Knudsen, W. Hamilton, M. Proks, M. Lykkegaard, A. V. Nielsen, A. Trusina, J. M. Brickman

This study shows ESRRB supports pluripotency when NANOG is present but promotes a primitive endoderm identity when NANOG is absent, with their stoichiometry influencing differentiation.

bioRxiv · Sep 20, 2022Cell Biology

Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress

A. Igbaria, P. I. Merksamer, A. Trusina, F. Tilahun, J. R. Johnson, O. Brandman, N. J. Krogan, J. S. Weissman, F. R. Papa

The paper identifies a chaperone-mediated process that refuxes properly folded ER proteins to the cytosol during ER stress, functioning parallel to ERAD.

bioRxiv · Mar 12, 2019Cell Biology

Theoretical Tool Bridging Cell Polarities with Development of Robust Morphologies

S. B. Nissen, S. Ronhild, A. Trusina, K. Sneppen

The paper proposes a theoretical framework linking cell polarities to morphological stability and diversity, suggesting polar adhesion strength and proliferation rates as key factors.

eLife · Nov 27, 2018Peer-reviewedBiophysics