Author

A. Tsirigotaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Economou· 2 shared S. Karamanou· 2 shared A. Doemling· 1 shared A. Portaliou· 1 shared A. Vorobieva· 1 shared D. A. Griffith· 1 shared D. Smets· 1 shared G. Gouridis· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

A. Economou

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2 papers

Recent·Most cited

Evolutionary adaptation of the folding pathway for secretability

D. Smets, A. Tsirigotaki, J. H. Smit, S. Krishnamurthy, A. Portaliou, A. Vorobieva, W. Vranken, S. Karamanou, A. Economou

This study identifies structural features that delay folding in secretory proteins, enabling their translocation, by comparing PpiA and PpiB.

bioRxiv · Apr 3, 2022 · PreprintBiochemistry

Evolution of structural dynamics in bilobed proteins

G. Gouridis, Y. Muthahari, M. de Boer, K. Tassis, A. Tsirigotaki, N. Zijlstra, N. Eleftheriadis, R. Xu, M. Zacharias, D. A. Griffith, Y. Sugijo, A. Doemling, S. Karamanou, A. Economou, T. Cordes

The paper investigates how structural dynamics in bilobed proteins evolve, showing that modifications to the structural core enable functional diversification through altered interdomain interactions and substrate specificity.

bioRxiv · Oct 19, 2020 · PreprintBiophysics