Author

A. V. Rorick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:non-human primate· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. A. Cohen· 2 shared J. R. Keeffe· 2 shared P. J. Bjorkman· 2 shared P. N. P. Gnanapragasam· 2 shared A. I. Ramsingh· 1 shared A. J. Greaney· 1 shared A. K. Chakraborty· 1 shared A. P. West· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

A. A. Cohen

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2 papers

Recent·Most cited

Designed mosaic nanoparticles enhance cross-reactive immune responses in mice

E. Wang, A. A. Cohen, L. F. Caldera, J. R. Keeffe, A. V. Rorick, Y. M. Aida, P. N. P. Gnanapragasam, P. J. Bjorkman, A. K. Chakraborty

The paper designs mosaic nanoparticles with SARS-like betacoronavirus RBDs to enhance cross-reactive immune responses in mice, finding that mosaic-7COM elicits stronger responses against zoonotic sarbecoviruses and Omicrons.

bioRxiv · Feb 28, 2024Immunology

Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals

A. A. Cohen, J. R. Keeffe, A. Schiepers, S. E. Dross, A. J. Greaney, A. V. Rorick, H. Gao, P. N. P. Gnanapragasam, C. Fan, A. P. West, A. I. Ramsingh, J. H. Erasmus, J. D. Pata, H. Muramatsu, N. Pardi, , P. J. Bjorkman

The paper shows mosaic-8b nanoparticles induce broader cross-reactive antibodies than homotypic ones, even in pre-vaccinated animals, suggesting potential for improved vaccine design against emerging sarbecoviruses.

bioRxiv · Feb 8, 2024Immunology