Author

A. Valdespino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. Dann· 2 shared D. Yang· 2 shared L. Robinson-Mailman· 2 shared M. R. Rosner· 2 shared A. Gonzalez· 1 shared A. Mohamed· 1 shared D. M. Renner· 1 shared D. Silva· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

C. Dann

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Analysis of gene expression heterogeneity reveals therapeutic targets and novel regulators of metastasis

D. Yang, C. Dann, A. Valdespino, L. Robinson-Mailman, M. Henn, M. Chen, G. Balazsi, M. R. Rosner

The paper identifies therapeutic targets and novel metastasis regulators by analyzing gene expression heterogeneity in triple-negative breast cancer using single-cell RNA sequencing.

bioRxiv · Dec 16, 2022 · PreprintCancer Biology

SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells

L. C. Nguyen, D. M. Renner, D. Silva, D. Yang, N. Parenti, K. M. Medina, V. Nicolaescu, H. Gula, N. Drayman, A. Valdespino, A. Mohamed, C. Dann, K. Wannemo, L. Robinson-Mailman, A. Gonzalez, , S. R. Weiss

This study compares how SARS-CoV-2 and other betacoronaviruses activate the IRE1α/XBP1 ER stress pathway in human lung cells, finding that SARS-CoV-2 only partially activates it, potentially evading host immune detection.

bioRxiv · Dec 30, 2021 · PreprintMicrobiology