Author

A. Vanden Broeck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Ecology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 4 Assay:cryo-EM· 4 Organism:human· 3 Approach:microscopy & imaging analysis· 2 Research Focus:protein structure prediction· 2 Organism:E. coli· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

S. Klinge· 3 shared V. Lamour· 2 shared A. Van Braeckel· 1 shared B. Wang· 1 shared C. Bedez· 1 shared C. Lotz· 1 shared C. Sawyers· 1 shared D. Bonte· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersBiochemistry

S. Klinge

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Principles of human pre-60S biogenesis

A. Vanden Broeck, S. Klinge

The paper reports cryo-EM structures of human pre-60S particles, revealing mechanisms of ribosome assembly involving protein interaction hubs and RNA processing.

bioRxiv · Mar 14, 2023Biochemistry

A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation

Z. Sanghai, R. Piwowarczyk, A. Vanden Broeck, S. Klinge

The paper reports the cryo-EM structure of a co-transcriptional large ribosomal subunit assembly intermediate, revealing how quality control is established during ribosome biogenesis.

bioRxiv · Mar 2, 2023Biophysics

Asymmetrical gene flow between coastal and inland dunes in a threatened digger wasp

F. Batsleer, M. Gallin, M. Delafonteyne, D. Dekeukeleire, F. T'Jollyn, P. Vantieghem, A. Vanden Broeck, J. Mergeay, D. Maes, D. Bonte

This study examines gene flow asymmetry between coastal and inland dune habitats of the digger wasp Bembix rostrata, finding stronger genetic structure in inland populations and directional gene flow from coast to inland.

bioRxiv · Sep 20, 2022Ecology

Allosteric interactions prime androgen receptor dimerization and activation

E. Wasmuth, A. Vanden Broeck, J. R. LaClair, E. A. Hoover, K. E. Lawrence, N. Paknejad, K. J. Pappas, D. Matthies, B. Wang, W. Feng, P. A. Watson, J. C. Zinder, W. Karthaus, M. J. de la Cruz, R. K. Hite, , C. Sawyers

This study identifies allosteric interactions that prime androgen receptor dimerization and activation, revealing structural and functional mechanisms relevant to development and disease.

bioRxiv · Feb 20, 2022Biochemistry

Structural basis for the allosteric regulation of Human Topoisomerase 2α

A. Vanden Broeck, C. Lotz, R. Drillien, C. Bedez, V. Lamour

This study presents cryo-EM structures of human Top2 nucleoprotein complexes, revealing molecular details of allosteric regulation and the role of the C-terminal domain.

bioRxiv · Aug 23, 2020Biochemistry

Reintroduced native Populus nigra in restored floodplain reduces spread of exotic poplar species

A. Vanden Broeck, K. Cox, A. Van Braeckel, S. Neyrinck, N. De Regge, K. Van Looy

This study shows that reintroducing native Populus nigra in restored floodplains reduces the spread of exotic poplar species by outcompeting their gene flow.

bioRxiv · Jul 2, 2020Ecology

Cryo-EM structure of the complete E. coli DNA Gyrase nucleoprotein complex

A. Vanden Broeck, J. Ortiz, V. Lamour

This study determines the cryo-EM structure of E. coli DNA Gyrase bound to DNA and an antibiotic, revealing its architecture and providing insights into its function and antibiotic binding.

bioRxiv · Jul 11, 2019Biochemistry