Author

J. R. LaClair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. R. Wasik· 2 shared C. R. Parrish· 2 shared K. N. Barnard· 2 shared A. Vanden Broeck· 1 shared A. Varki· 1 shared B. K. Alford-Lawrence· 1 shared B. K. Lawrence· 1 shared B. Wang· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

B. R. Wasik

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Allosteric interactions prime androgen receptor dimerization and activation

E. Wasmuth, A. Vanden Broeck, J. R. LaClair, E. A. Hoover, K. E. Lawrence, N. Paknejad, K. J. Pappas, D. Matthies, B. Wang, W. Feng, P. A. Watson, J. C. Zinder, W. Karthaus, M. J. de la Cruz, R. K. Hite, , C. Sawyers

This study identifies allosteric interactions that prime androgen receptor dimerization and activation, revealing structural and functional mechanisms relevant to development and disease.

bioRxiv · Feb 20, 2022Biochemistry

The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

K. N. Barnard, B. K. Alford-Lawrence, D. W. Buchholz, B. R. Wasik, J. R. LaClair, H. Yu, R. Honce, S. Ruhl, P. Pajic, E. K. Daugherity, X. Chen, S. Schultz-Cherry, H. C. Aguilar, A. Varki, C. R. Parrish

This study examines how modified sialic acids in mucus and erythrocytes affect influenza A virus HA and NA functions, finding that these modifications inhibit viral binding and cleavage.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Expression of 9-O- and 7,9-O-acetyl modified sialic acids in cells and their effects on influenza viruses

K. N. Barnard, B. R. Wasik, J. R. LaClair, W. Weichert, B. K. Lawrence, C. R. Parrish

The paper examines the expression and effects of 9-O- and 7,9-O-acetyl modified sialic acids on influenza virus infections in human and canine cells.

bioRxiv · May 25, 2019Cell Biology