Author

M. Muschen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. Izraeli· 2 shared A. Borkhard· 1 shared A. M. Savino· 1 shared A. Nagler· 1 shared A. P. Wiita· 1 shared A. Rein Gil· 1 shared A. Vogt· 1 shared C. Hong· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

S. Izraeli

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2 papers

Recent·Most cited

Signaling input from divergent pathways subverts malignant B-cell transformation

L. N. Chan, M. A. Murakami, M. E. Robinson, R. Caeser, T. Sadras, J. Lee, K. N. Cosgun, K. Kume, V. Khairnar, G. Xiao, M. Ahmed, E. Aghania, G. Deb, C. Hurtz, S. Shojaee, , M. Muschen

This study shows that malignant B-cell transformation requires convergence on a single oncogenic pathway, while divergent pathways can subvert transformation and are targets for new therapeutic strategies.

bioRxiv · Mar 12, 2020Cancer Biology

An instructive role for IL7RA in the development of human B-cell precursor leukemia.

I. Geron, A. M. Savino, N. Tal, H. Fishman, J. Brown, V. Turati, C. James, J. Sarno, Y. N. Lee, A. Rein Gil, Y. Birger, I. Muler, M. Hameiri-Grossman, V. Marcu-Malina, O. Parnas, , S. Izraeli

This study shows that aberrant IL7RA signaling in human hematopoietic progenitors leads to B-cell differentiation arrest and Ph-like BCP-ALL development in mice.

bioRxiv · Jan 27, 2020 · PreprintCancer Biology