Author

H.-W. Mittruecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Kaffke· 1 shared A. Peters· 1 shared A. Volmari· 1 shared A. W. Lohse· 1 shared C. F. Krebs· 1 shared H. Wang· 1 shared H.-J. Paust· 1 shared I. Prinz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Kaffke

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2 papers

Recent·Most cited

The integrated stress response/eIF2α pathway controls cytokine production in tissue-resident memory CD4+ T cells

N. Asada, P. Ginsberg, H.-J. Paust, N. Song, J.-H. Riedel, J.-E. Turner, A. Peters, A. Kaffke, J. Engesser, H. Wang, Y. Zhao, P. Gild, R. Dahlem, S. Das, Z. Ignatova, , U. Panzer

This study shows that the ISR/eIF2α pathway regulates cytokine mRNA translation in Trm cells, limiting their activity in homeostasis but enabling rapid response during inflammation or autoimmunity.

bioRxiv · Jan 26, 2024Immunology

Leukocyte-derived High-mobility group box 1 controls innate immune responses against Listeria monocytogenes.

A. Volmari, K. Foelsch, K. Yan, M. Qi, K. Bartels, S. Kondratowicz, M. Boettcher, M. Nishibori, K. Liu, R. F. Schwabe, A. W. Lohse, S. Huber, H.-W. Mittruecker, P. Huebener

This study shows that HMGB1 from leukocytes is critical for immune responses against Listeria monocytogenes, while hepatocyte HMGB1 is not essential for moderate infections but may contribute to excessive inflammation in severe cases.

bioRxiv · Oct 8, 2019 · PreprintImmunology