Author

Aaron D. Showalter

Eli Lilly (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alfonso EspadaiD· 1 shared An-Ping Yu· 1 shared David B. WainscottiD· 1 shared Eamonn ReadingiD· 1 shared Howard B. BroughtoniD· 1 shared Jakub SýsiD· 1 shared Joseph D Ho· 1 shared Kyle W. SloopiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Alfonso EspadaORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Structural dynamics underlying agonist activation of a GLP-1R-Gs precoupled complex

Jakub Sýs, Joseph D Ho, Aaron D. Showalter, An-Ping Yu, David B. Wainscott, Veronica Laos, Howard B. Broughton, Kyle W. Sloop, Alfonso Espada, Eamonn Reading

This study uses hydrogen-deuterium exchange mass spectrometry to analyze how non-peptide agonists and endogenous ligands modulate structural dynamics in a pre-coupled GLP-1R-Gs complex, revealing patterns linked to receptor activation.

bioRxiv · Aug 4, 2026 · PreprintBiochemistry