Immune Niche Formation in Engineered Mouse Models Reveals Mechanisms of Tumor Dormancy
Abdul Ahad, Feng Leng, Hiroshi Ichise, Edward C. Schrom, Jae Young So, Carter Sellner, Yang Gu, Wenjuan Wang, Kieu C. Do, Woo Yong Park, Rachel Yang, Karen Wolcott, Ferenc Livák, Michael J. Kruhlak, Olga N. Aprelikova, , Yang Li
This study identifies immune-tumor interactions that drive tumor dormancy in a mouse model, highlighting IFN-γ-KLF4-SLURP1 and CD200-CD200R1 pathways.
bioRxiv · Apr 16, 2025 · PreprintCancer Biology