A novel membrane stress-response that blocks chromosomal replication by targeting the DnaA initiator via the ClpP protease
Alabi Gbolahan, Tong Li, Rishit Saxena, karen Wolcott, Aamna Sohail, Ishika Ahmad, Dhruba K. Chattoraj, Elliott Crooke, Rahul Saxena
This paper identifies a novel membrane stress-response in E. coli that blocks DNA replication by targeting DnaA via ClpP protease, independent of Lon and (p)ppGpp.
Journal of Bacteriology · Jun 24, 2025Peer-reviewedMicrobiology