Author

Ada J. Lin

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Haakon B. NygaardiD· 2 shared Stefan WendtiD· 2 shared Alice BuonfiglioliiD· 1 shared Brian A. MacVicariD· 1 shared Brooke L. LatouriD· 1 shared Christopher J. GroteniD· 1 shared Christopher Lee· 1 shared Da Young Kong· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Haakon B. NygaardORCID

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2 papers

Recent·Most cited

A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis

Stefan Wendt, Ada J. Lin, Sarah N. Ebert, Declan J. Brennan, Wenji Cai, Yanyang Bai, Da Young Kong, Stefano Sorrentino, Christopher J. Groten, Christopher Lee, Jonathan Frew, Hyun B. Choi, Konstantina Karamboulas, Mathias Delhaye, Ian R. Mackenzie, , Haakon B. Nygaard

This paper uses a 3D human iPSC-derived neurosphere model to study how microglia modify cellular responses to chronic amyloidosis, revealing their role in reducing neurotoxicity and regulating AD-associated gene expression.

Journal of Neuroinflammation · Apr 24, 2025Peer-reviewedNeuroscience

A microglia-containing cerebral organoid model to study early life immune challenges

Alice Buonfiglioli, Raphael Kübler, Roy D. Missall, Renske de Jong, Stephanie Chan, Verena Claudia Haage, Stefan Wendt, Ada J. Lin, Daniele Mattei, Mara Graziani, Brooke L. Latour, Frederieke A. J. Gigase, Rebecca Chiu, Ya Zhang, Haakon B. Nygaard, , Lot D. de Witte

This paper introduces a cerebral organoid model with integrated microglia to study how inflammatory stimuli and microglial presence affect neurodevelopment and neurodevelopmental disorders.

bioRxiv · May 24, 2024Neuroscience