Single-cell multiomic approaches define a gradual, spatially-regulated epigenetic and transcriptional transition from embryonic to adult neural stem cells
Beatrix S. Wang, Konstantina Karamboulas, Nareh Tahmasian…·Freda D. Miller
Author
Hospital for Sick Children
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Beatrix S. Wang, Konstantina Karamboulas, Nareh Tahmasian…·Freda D. Miller
Sruthi Purushothaman, Sandeep Saxena, Christine Eisner…·Freda D. Miller
The paper identifies the nail mesenchyme's role in creating a BMP-rich ligand environment that drives regeneration over fibrosis in digit tip regeneration.
Sarah N. Ebert, Christine Eisner, Konstantina Karamboulas…·Freda D. Miller
The paper uses single-cell RNA-seq and spatial transcriptomics to identify and characterize distinct cell types at the murine brain interface, revealing their molecular features and potential interactions.
Stefan Wendt, Ada J. Lin, Sarah N. Ebert…·Haakon B. Nygaard
This paper uses a 3D human iPSC-derived neurosphere model to study how microglia modify cellular responses to chronic amyloidosis, revealing their role in reducing neurotoxicity and regulating AD-associated gene expression.