Martin Dieter Baaske

This paper introduces a method combining rotational and translational single-particle tracking to analyze nanoscale dynamics, showing it reveals distinct biophysical features of cellular compartments.

This study reveals that the bacterial SMC Wadjet complex uses loop extrusion to specifically recognize and cleave plasmid DNA, establishing loop extrusion as a conserved mechanism across SMC complexes.

This study shows that dimeric SMC motors switch extrusion directionality based on DNA tension, with cohesin being constitutively biased toward one-sided extrusion.