Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in liver of healthy and obese mice
Keigo Morita, Atsushi Hatano, Toshiya Kokaji, Hikaru Sugimoto, Takaho Tsuchiya, Haruka Ozaki, Riku Egami, Dongzi Li, Akira Terakawa, Satoshi Ohno, Hiroshi Inoue, Yuka Inaba, Yutaka Suzuki, Masaki Matsumoto, Masatomo Takahashi, , Shinya Kuroda
The paper examines how obesity disrupts the temporally ordered metabolic network in the liver during starvation, revealing structural robustness but temporal vulnerability.
bioRxiv · Jun 17, 2024 · PreprintSystems Biology