Author

Riku Egami

The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Systems Biology· 4

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Research Focus:gene regulatory network inference· 4 Organism:mouse· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Assay:metabolomics· 1

Frequent Co-Authors

Akiyoshi HirayamaiD· 4 shared Atsushi HatanoiD· 4 shared Hiroshi InoueiD· 4 shared Satoshi OhnoiD· 4 shared Shinya KurodaiD· 4 shared Tomoyoshi SogaiD· 4 shared Toshiya KokajiiD· 4 shared Dongzi LiiD· 3 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Akiyoshi HirayamaORCID

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4 papers

Recent·Most cited

Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in liver of healthy and obese mice

Keigo Morita, Atsushi Hatano, Toshiya Kokaji, Hikaru Sugimoto, Takaho Tsuchiya, Haruka Ozaki, Riku Egami, Dongzi Li, Akira Terakawa, Satoshi Ohno, Hiroshi Inoue, Yuka Inaba, Yutaka Suzuki, Masaki Matsumoto, Masatomo Takahashi, , Shinya Kuroda

The paper examines how obesity disrupts the temporally ordered metabolic network in the liver during starvation, revealing structural robustness but temporal vulnerability.

bioRxiv · Jun 17, 2024 · PreprintSystems Biology

Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

Yunfan Bai, Keigo Morita, Toshiya Kokaji, Atsushi Hatano, Satoshi Ohno, Riku Egami, Yifei Pan, Dongzi Li, Katsuyuki Yugi, Saori Uematsu, Hiroshi Inoue, Yuka Inaba, Yutaka Suzuki, Masaki Matsumoto, Masatomo Takahashi, , Shinya Kuroda

The paper compares metabolic dysregulation in obese mice during feeding and fasting using multi-omics data, revealing opposite metabolic shifts linked to obesity.

iScience · Feb 26, 2024Peer-reviewedSystems Biology

In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states

Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken‐ichi Hironaka, Yuki Ito, Riku Egami, Saori Uematsu, Akira Terakawa, Yifei Pan, Hideki Maehara, Dongzi Li, , Shinya Kuroda

This study uses multiomic analysis of skeletal muscle in obese and healthy mice to reveal differences in metabolic regulation by metabolites and genes after glucose administration.

Scientific Reports · Aug 12, 2022Peer-reviewedSystems Biology

Trans-omic analysis reveals allosteric and gene regulation-axes for altered glucose-responsive liver metabolism associated with obesity

Toshiya Kokaji, Atsushi Hatano, Yuki Ito, Katsuyuki Yugi, Miki Eto, Satoshi Ohno, Masashi Fujii, Ken‐ichi Hironaka, Riku Egami, Hiroshi Inoue, Shinsuke Uda, Hiroyuki Kubota, Yutaka Suzuki, Kazutaka Ikeda, Makoto Arita, , Shinya Kuroda

The paper analyzes trans-omic data from healthy and obese mice to reveal that glucose-responsive liver metabolism is regulated by rapid changes in metabolites and gene expression in the healthy state, and by slow transcriptional regulation in the obese state.

bioRxiv · May 31, 2019 · PreprintSystems Biology