Author

Alexandra L. Howell

Cardiff UniversityPrimary ORCID profile (0000-0002-2362-2596 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Alexandra L. HowelliD3 papers · Dartmouth College

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Huerta UribeiD· 1 shared Andrew E. HoganiD· 1 shared Ardena BerishaiD· 1 shared Benjamin F. CravattiD· 1 shared Benjamin JenkinsiD· 1 shared Chloe MoscropiD· 1 shared David K. FinlayiD· 1 shared David P. SumptoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alejandro Huerta UribeORCID

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Author profile →

1 paper

Recent·Most cited

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity

Benjamin Jenkins, Yasmin R Jenkins, Fernando M. Ponce-Garcia, Chloe Moscrop, Iain A. Perry, Matthew D. Hitchings, Alejandro Huerta Uribe, Federico Bernuzzi, Simon Eastham, J. Cronin, Ardena Berisha, Alexandra L. Howell, Joanne E. Davies, Julianna Blagih, Douglas James Veale, , Nicholas Jones

This paper shows that inhibiting ABHD11 reduces T cell cytokine production and alleviates autoimmunity by altering sterol metabolism and LXR activation.

bioRxiv · Mar 19, 2025 · PreprintImmunology