Author

Simon Eastham

University of BristolORCID 0009-0005-3316-310XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chloe MoscropiD· 2 shared Gareth Wyn JonesiD· 2 shared Aisling S. Morrin· 1 shared Alejandro Huerta UribeiD· 1 shared Alexandra L. Howell· 1 shared Alison Young· 1 shared Amy WardiD· 1 shared Andrew D. DickiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Chloe MoscropORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 17, 2026

Inflammatory arthritis disrupts ocular immune privilege by compromising blood-retinal barrier integrity and promoting uveitogenic T cell recruitment

Simon Eastham, Amy Ward, Chloe Moscrop…·Gareth Wyn Jones

This study shows inflammatory arthritis disrupts the blood-retinal barrier and promotes T cell recruitment to the eye, increasing susceptibility to uveitis without causing overt ocular disease.

DOI 10.64898/2026.07.13.738174

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 19, 2025

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity

Benjamin Jenkins, Yasmin R Jenkins, Fernando M. Ponce-Garcia…·Nicholas Jones

This paper shows that inhibiting ABHD11 reduces T cell cytokine production and alleviates autoimmunity by altering sterol metabolism and LXR activation.

DOI 10.1101/2025.03.19.643996

humanmouse

𝕏 PostBluesky