Author

Alexandre TRICHIES

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adriana Figueroa GarciaiD· 1 shared Caroline Evrard· 1 shared Catherine BaudiD· 1 shared Frédéric ChecleriD· 1 shared Hanane Abouelfarah· 1 shared Jean‐Michel SaliouiD· 1 shared Lisa BRISOIRE· 1 shared Luc BuéeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Adriana Figueroa GarciaORCID

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1 paper

Recent·Most cited

APP metabolism is regulated by p97/VCP through an autophagy and endolysosome-dependent mechanism

Adriana Figueroa Garcia, Lisa BRISOIRE, Catherine Baud, Raphaëlle Caillierez, Sabiha Eddarkaoui, Caroline Evrard, Jean‐Michel Saliou, Séverine Bégard, Mathilde Coevoet, Hanane Abouelfarah, Alexandre TRICHIES, Luc Buée, Patricia Melnyk, Valérie Vingtdeux, Raphaëlle Pardossi‐Piquard, , Nicolas Sergeant

This study shows that p97/VCP regulates APP metabolism by controlling its trafficking and autophagy-dependent degradation of APP-CTFs, linking it to Alzheimer's disease pathology.

bioRxiv · Feb 4, 2026 · PreprintCell Biology