Author
Centre National de la Recherche ScientifiqueORCID 0000-0003-2098-1750Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Adriana Figueroa Garcia, Lisa BRISOIRE, Catherine Baud…·Nicolas Sergeant
This study shows that p97/VCP regulates APP metabolism by controlling its trafficking and autophagy-dependent degradation of APP-CTFs, linking it to Alzheimer's disease pathology.
Fanny Eysert, Véronique Legros, Anne-Sophie Gay…·Mounia Chami
This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.
Arnaud Mary, Samantha Barale, Fanny Eysert…·Mounia Chami
This study shows that impairing the AMPK-ULK1 cascade in Alzheimer's disease leads to mitochondrial dysfunction and AD-related changes, which are improved by metformin treatment.
Fanny Eysert, Paula Fernanda Kinoshita, Julien Lagarde…·Mounia Chami
The paper examines mitochondrial alterations in fibroblasts from Alzheimer's disease patients and links them to clinical hallmarks and cognitive decline.
Laura García‐González, Jean‐Michel Paumier, Laurence Louis…·Santiago Rivera
This study identifies MT5-MMP's role in regulating APP processing and Aβ levels through proteolytic and non-proteolytic mechanisms in Alzheimer's disease.
Fanny Eysert, Audrey Coulon, Emmanuelle Boscher…·Julien Chapuis
The paper identifies FERMT2 as a key modulator of axon guidance and synaptic plasticity in an APP-dependent manner, linking its genetic risk variant to Alzheimer's disease through miRNA regulation.
Devrim Kilinc, Anaïs-Camille Vreulx, Tiago Mendes…·Jean‐Charles Lambert
The paper develops a microfluidic co-culture model to study Aβ1-42-induced synaptotoxicity and shows Pyk2 overexpression in postsynaptic neurons protects against it.