Author

Hao Xu

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 1 Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alan G. GutierreziD· 1 shared Alexander Martinez‐FundichelyiD· 1 shared Amanda C. Lorentzian· 1 shared Ana Molina· 1 shared Andrea SboneriD· 1 shared Anisha B. Tehim· 1 shared Beijing CheniD· 1 shared Benjamin J. RaphaeliD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperSystems Biology

Alan G. GutierrezORCID

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5 papers

Recent·Most cited

Cell-Type-Specific Surfaceome Profiling of 100-500 Isolated Cells using a Droplet-Based Magnetic Affinity Purification System

Amanda C. Lorentzian, Juliet M. Bartleson, Terence Ho, Hao Xu, Christopher B. Bullock, Zhichang Yang, Alan G. Gutierrez, Meena Choi, Tommy K. Cheung, Christopher M. Rose, Hua Zhang, William T. Yewdell, Ying Zhu

The paper develops nanoMAPS, a droplet-based magnetic affinity purification system for surfaceome profiling of 100-500 cells, improving recovery and reducing non-specific absorption.

Nature Communications · Sep 18, 2026Peer-reviewedSystems Biology

Indazolone-Based Molecular Glue Degraders as a Tunable Platform for Reprogramming Cereblon Substrate Specificity

Hui‐Jun Nie, Jiamin Wang, Hao Xu, Yin-Jue Zhou, Guang‐Liang Yin, Xiaomim Xu, Gaoya Xu, Beijing Chen, Xian Li, Xiaobei Hu, Yubo Zhou, Jia Li, Chen Xiaohua

This paper introduces an indazolone-based platform for CRBN molecular glue degraders, enabling tunable substrate specificity and broad therapeutic potential.

bioRxiv · Mar 25, 2026 · PreprintBiochemistry

Genomic alterations in the YAP/TAZ pathway are associated with stem cell-like castration-resistant prostate cancer

Marjorie L. Roskes, Alexander Martinez‐Fundichely, Sandra M. Cohen, Metin Balaban, Chen Khuan Wong, Weiling Li, Tonatiuh A. Gonzalez, Anisha B. Tehim, Hao Xu, Shahd ElNaggar, Matthew A. Myers, Rohan Bareja, Princesca Dorsaint, Kathryn Gorski, Muhammad Imran Asad, , Ekta Khurana

The paper identifies genomic alterations in the YAP/TAZ pathway associated with stem cell-like castration-resistant prostate cancer using transcriptomic and whole-genome sequencing data.

medRxiv · Jul 1, 2025 · PreprintGenetic & Genomic Medicine

Recombination shapes the diversification of the wtf meiotic drivers

Yan Wang, Hao Xu, Qinliu He, Zhiwei Wu, Zhen Hui Gong, Guan‐Zhu Han

The paper shows that recombination generates new meiotic drivers by creating poisons not detoxified by parental antidotes, driving diversification of wtf genes in fission yeast.

bioRxiv · Sep 4, 2024Evolutionary Biology

PCPE2 and SR-BI Partner to Impact Accumulation of Fat in Mice

Hao Xu, Sushma Kaul, Rachel Kallinger, Michael J. Thomas, Rebecca L. Schill, Daisy Sahoo, Mary G. Sorci-Thomas

This study shows that PCPE2 and SR-BI interact to facilitate CE transport from HDL into cells, and their absence disrupts lipid transport in mice.

bioRxiv · Apr 9, 2018 · PreprintBiochemistry