Author

Amanda E Kroesen

Stowers Institute for Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam J. MeadiD· 1 shared Allison R. ScottiD· 1 shared Anoja G. PereraiD· 1 shared Athanasios Ploumakis· 1 shared Carlo RinaldiiD· 1 shared Fei CheniD· 1 shared Hua Li· 1 shared Ioannis VlachosiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

Adam J. MeadORCID

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Author profile →

2 papers

Recent·Most cited

In situ identification of pre-hematopoietic stem cells and their niche

Xinjian Mao, Ning Zhang, Laura F. Bennett, Xi He, Allison R. Scott, Kate Hall, Kaitlyn Petentler, Seth Malloy, Shengping Huang, Amanda E Kroesen, Sean McKinney, Athanasios Ploumakis, Zhe Yang, Ruochen Dong, Jose Emmanuel Javier, , Linheng Li

The paper identifies pre-hematopoietic stem cells and their niche using spatial transcriptomics in the AGM region, revealing spatial signaling patterns and cellular interactions that support HSC development.

bioRxiv · Oct 6, 2026 · PreprintDevelopmental Biology

Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology

Muhammad Hanifi, Perihan Seda Ateş, Sean Wen, Mathieu Fischer, Amanda E Kroesen, Zulin Yu, Matthew Wood, Supat Thongjuea, Adam J. Mead, Tudor A. Fulga, Carlo Rinaldi, Tatjana Sauka‐Spengler

This paper develops CRISPR-Lock, a CRISPR/dCas13 RNA blocker that disrupts miRNA-target interactions and rescues DM1 pathology by correcting splicing biomarkers and reducing nuclear foci.

bioRxiv · Sep 16, 2024 · PreprintBioengineering