Author

Andrea Ahles

Technical University of Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anika ReifschneideriD· 1 shared Anja CapelliD· 1 shared Björn BartelsiD· 1 shared Christian HaassiD· 1 shared Christine Van BroeckhoveniD· 1 shared Claudia Krenner· 1 shared Dieter EdbaueriD· 1 shared Dominik PaquetiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anika ReifschneiderORCID

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1 paper

Recent·Most cited

Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

Sophie Robinson, Marvin Reich, Maria‐Teresa Mühlhofer, Katrin Buschmann, Eline Wauters, Quirin Mühlhofer, Georg Werner, Andrea Ahles, Stefan Hanns Engelhardt, Claudia Krenner, Björn Bartels, Simon Gutbier, Anika Reifschneider, Henrick Riemenschneider, Thomas Reinheckel, , Anja Capell

This study shows that reduced progranulin leads to increased legumain activity, which promotes TDP-43 pathology in FTLD, suggesting legumain as a therapeutic target.

bioRxiv · Jan 16, 2024 · PreprintNeuroscience