Author
German Center for Neurodegenerative DiseasesORCID 0009-0003-9633-7360Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Geraldine Rodschinka, Sergio Forcelloni, Felix M Kühner…·Danny D. Nedialkova
The paper compares CRISPRi screens in human stem cells and their derivatives to show cell type-dependent roles of translation-coupled quality control factors.
Francesca Simonetti, Weijia Zhong, Saskia Hutten…·Dorothee Dormann
This study shows that TDP-43 and Tau directly interact, promoting co-condensation but reducing Tau fibril formation and seeding.
Sophie Robinson, Marvin Reich, Maria‐Teresa Mühlhofer…·Anja Capell
This study shows that reduced progranulin leads to increased legumain activity, which promotes TDP-43 pathology in FTLD, suggesting legumain as a therapeutic target.
Henrick Riemenschneider, Qiang Guo, Jakob Maximilian Bader…·Dieter Edbauer
This study identifies TDP-25 inclusions as sequestering proteasomes, leading to proteostasis impairment in ALS/FTD.