Author

Andrew Lytle

BC Cancer Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Adèle TeleniusiD· 3 shared Andrew J. L. RothiD· 3 shared Christian SteidliD· 3 shared Eric LeeiD· 3 shared Shaocheng WuiD· 3 shared Shinya RaiiD· 3 shared Tomohiro AokiiD· 3 shared Yifan YiniD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Adèle TeleniusORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Developmental origins of thymic B-cell lymphomas

Shinya Rai, Yifan Yin, Manabu Fujisawa, Makoto Kishida, Michael Yu Li, Jeffrey Niu, Aixiang Jiang, Laura K. Hilton, Amos Fong, Gerben Duns, Adèle Telenius, Barbara Meissner, Merrill Boyle, Hisae Nakamura, Alexandra Roos, , Christian Steidl

This study identifies a thymus-specific B-cell differentiation program linked to thymic B-cell lymphomagenesis through single-cell multiomics and spatial profiling.

bioRxiv · Oct 20, 2026 · PreprintCancer Biology

Single-cell spatial multi-omic characterization of the tumour microenvironment in transformed follicular lymphoma

Shaocheng Wu, Eric Lee, Anne-Sophie Fratzscher, Andrew Lytle, Spencer D. Martin, Tina Hsu, Adèle Telenius, Yifan Yin, Amos Fong, Shinya Rai, Manuba Fujisawa, Honor Cheung, Samuel A. J. R. Aparicio, David D. Huntsman, Tomohiro Aoki, , Andrew J. L. Roth

The paper uses multi-omic single-cell spatial techniques to study FL transformation, finding spatial shifts in B-cell neighborhoods and immunomodulatory interactions linked to disease progression.

bioRxiv · Aug 18, 2026 · PreprintBioinformatics

Multidimensional characterization of cellular ecosystems in Hodgkin lymphoma

Tomohiro Aoki, Gerben Duns, Shinya Rai, Aixiang Jiang, Andrew Lytle, Yifan Yin, Makoto Kishida, Michael Yu Li, Denise Smorra, Laura K. Hilton, Stefan Alig, Mohammad Shahrokh Esfahani, Clémentine Sarkozy, Stacy S. Hung, Katy Milne, , Christian Steidl

This study identifies four molecular subtypes of Hodgkin lymphoma using multimodal data, revealing distinct clinical features and immune ecosystem dynamics.

bioRxiv · Mar 18, 2025 · PreprintCancer Biology