Single-cell spatial multi-omic characterization of the tumour microenvironment in transformed follicular lymphoma
Shaocheng Wu, Eric Lee, Anne-Sophie Fratzscher, Andrew Lytle, Spencer D. Martin, Tina Hsu, Adèle Telenius, Yifan Yin, Amos Fong, Shinya Rai, Manuba Fujisawa, Honor Cheung, Samuel A. J. R. Aparicio, David D. Huntsman, Tomohiro Aoki, , Andrew J. L. Roth
The paper uses multi-omic single-cell spatial techniques to study FL transformation, finding spatial shifts in B-cell neighborhoods and immunomodulatory interactions linked to disease progression.
bioRxiv · Aug 18, 2026 · PreprintBioinformatics