Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease
Mackenzie M. Thornton, Nicole Sommer, Mercedes B. Mcgonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim, Aakriti Chaturvedi, Johnny Dinh Phan, Anubhav Chakraborty, Praveen V. Chakravarthi, Sumedha Gunewardena, Mudit Tyagi, Jaya Talreja, Tao Wang, Pravin C. Singhal, , Madhulika Sharma
This study shows that Notch3 deletion reduces HIV-1 gene expression and systemic inflammation, improving outcomes in HIV-associated chronic kidney disease.
Disease Models & Mechanisms · Feb 1, 2025Peer-reviewedMolecular Biology