Molecular BiologybioRxivPreprint
VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
Ann Schirin Mirsanaye, Saskia Hoffmann, Melanie Bianca Weisser…·Niels Mailand
This paper identifies VCF1 as a novel p97 cofactor that enhances p97-UFD1-NPL4 interactions with ubiquitylated substrates, promoting proteasomal degradation.
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