Author

Saskia Hoffmann

University of CopenhagenORCID 0000-0003-4835-0504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ivo Alexander HendriksiD· 2 shared Michael Lund NielseniD· 2 shared Niels MailandiD· 2 shared Andreas MundiD· 1 shared Ann Schirin Mirsanaye· 1 shared Bente BenedictiD· 1 shared Blanca Lopez MendeziD· 1 shared Charu Jain· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Ivo Alexander HendriksORCID

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2 papers

Recent·Most cited

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedApr 22, 2024

Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation

Julio C.Y. Liu, Leena Ackermann, Saskia Hoffmann…·Niels Mailand

The paper identifies TOPORS as a SUMO-targeted ubiquitin ligase (STUbL) essential for SUMO-dependent DNA-protein crosslink repair and stress responses, showing its cooperative function with RNF4.

55 citationstop 1%

humanstatistical model

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 25, 2023

VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

Ann Schirin Mirsanaye, Saskia Hoffmann, Melanie Bianca Weisser…·Niels Mailand

This paper identifies VCF1 as a novel p97 cofactor that enhances p97-UFD1-NPL4 interactions with ubiquitylated substrates, promoting proteasomal degradation.

1 citation

humanexperimental assay

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