Author

Ann Semeao

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa BaccarellaiD· 1 shared Amanda B. MuiriD· 1 shared Ezuka Ogbolu· 1 shared Jarad BeersiD· 1 shared Joshua B. WechsleriD· 1 shared Judith R. KelseniD· 1 shared Kanak Kennedy· 1 shared Kelly A. WhelaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alyssa BaccarellaORCID

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1 paper

Recent·Most cited

Systemic Analysis of Patient Derived Esophageal Epithelial Organoid Model Reveals Cell State Heterogeneity and Conservation of Differentiation Hierarchy

Alyssa Baccarella, Yusen Zhou, Tatiana A. Karakasheva, Ravi Gautam, Megha Lal, Jarad Beers, Zoe Mrozek, Ann Semeao, Leena Mirchandani, Ryugo Teranishi, Takefumi Itami, Kanak Kennedy, Mark Mahon, Ezuka Ogbolu, Judith R. Kelsen, , Melanie A. Ruffner

The paper uses scRNA-seq to compare IL-13-treated esophageal organoids with EoE biopsies, revealing shared cell state heterogeneity and differentiation hierarchy dysregulation.

bioRxiv · Oct 30, 2026 · PreprintCell Biology