Activation of locus coeruleus noradrenergic neuronsrapidly drives homeostatic sleep pressure
Daniel Silverman, Changwan Chen, Shuang Chang, Lillie Bui, Yufan Zhang, Rishi Raghavan, Anna Jiang, April N. Le, Dana M. Darmohray, Jiao Sima, Xinlu Ding, Bing Li, Chenyan Ma, Yang Dan
The paper shows that activating locus coeruleus noradrenergic neurons increases sleep propensity after wakefulness, indicating their role in sleep pressure through functional fatigue.
Science Advances · Jan 17, 2025Peer-reviewedNeuroscience