The endoplasmic reticulum autophagy receptor TEX264 drives epidermal differentiation and is dysregulated in Darier disease
Christopher J. Johnson, Afua Tiwaa, Arti Parihar, Edwin Antonio, Brooke D. Lorenz, Reeteka Kudallur, Aaron Ramonett, Anthony Coon, Mrinal K. Sarkar, Johann Eli Gudjonsson, Cory L. Simpson
This study identifies TEX264 as a key driver of epidermal differentiation through reticulophagy, showing its dysregulation in Darier disease.
bioRxiv · Aug 5, 2025 · PreprintCell Biology