Author

Ariya Shiwram

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alejandro Álvarez-QuilóniD· 1 shared Artur VelosoiD· 1 shared C. Gary MarshalliD· 1 shared Cathy Caron· 1 shared Danielle HenryiD· 1 shared Elliot GoodfellowiD· 1 shared Frédéric ValléeiD· 1 shared Hye‐Yeon KimiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alejandro Álvarez-QuilónORCID

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1 paper

Recent·Most cited

A dual mechanism of sensitivity to PLK4 inhibition by RP-1664 in neuroblastoma

Isabel Soria‐Bretones, Matias Casás‐Selves, Elliot Goodfellow, Li Li, Cathy Caron, Ariya Shiwram, Hye‐Yeon Kim, Danielle Henry, Nancy Laterreur, Julian Bowlan, Alejandro Álvarez-Quilón, Frédéric Vallée, Artur Veloso, Jordan T.F. Young, Marc L. Hyer, , Michal Zimmermann

This study shows neuroblastoma cells are hypersensitive to PLK4 inhibitor RP-1664 due to dual mechanisms of centriole loss and amplification, leading to cell death.

bioRxiv · Feb 15, 2025 · PreprintCancer Biology