Author

Ashmita Baral

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ashkan JavaherianiD· 2 shared Nicholas A. Castello· 2 shared Steven M. FinkbeineriD· 2 shared Aaron D. GitleriD· 1 shared Alice Flynn Ford· 1 shared Anthony Q. VuiD· 1 shared Bo Lim Lee· 1 shared Bradley Class· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Ashkan JavaherianORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Opposing roles of p38α phosphorylation and arginine methylation in driving TDP-43 proteinopathy.

Mari Aikio, Hana M. Odeh, Heike J. Wobst, Bo Lim Lee, Úna Chan, Jocelyn C. Mauna, Korrie L. Mack, Bradley Class, Thomas A. Ollerhead, Alice Flynn Ford, Edward M. Barbieri, Ryan R. Cupo, Lauren E. Drake, Joshua L. Smalley, Yuan-Ta Lin, , James Shorter

This study identifies opposing roles of p38α phosphorylation and arginine methylation in TDP-43 proteinopathy, showing that phosphorylation promotes aggregation while methylation reduces it.

Cell Reports · Jan 1, 2025Peer-reviewedMolecular Biology

Modulation of RNA-dependent interactions in stress granules prevents persistent TDP-43 accumulation in ALS/FTD

Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu, Ashkan Javaherian, William E. Dowdle, Philippe Jolivet, Paul Bushway, Nicholas A. Castello, Ashmita Baral, Michelle Y. Chan, Jeremy W. Linsley, Drew A. Linsley, Mark A. Mercola, Steven M. Finkbeiner, Éric Lécuyer, , Gene Wei-Ming Yeo

The paper introduces VariantKey, a reversible numerical encoding for genetic variants, and presents compounds that inhibit stress granule formation and TDP-43 accumulation in ALS/FTD models.

Neuron · Jul 1, 2019Peer-reviewedNeuroscience