Proteomic Analysis Links Truncated Tau to Lysosome Motility, Autophagy and Endo-lysosomal Dysfunction
Despoina Goniotaki, Maximilian Hausherr, Steven Lynham, Ayushin Ale, George Chennell, Stefania Marcotti, Katrin Marcus, Wendy J. Noble, Diane P. Hanger, Graham Mathew Fraser, Deepak P. Srivastava
This study examines how Tau35 protein affects lysosomal function and autophagy, identifying early pathological changes linked to neurotoxicity in tauopathies.
Alzheimer s & Dementia · Dec 1, 2025Peer-reviewedNeuroscience