Author

Despoina Goniotaki

King's College LondonORCID 0000-0003-2120-8858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Diane P. HangeriD· 2 shared Wendy J. NobleiD· 2 shared Ayushin Ale· 1 shared Claire TroakesiD· 1 shared Deepak P. SrivastavaiD· 1 shared Francesco TamagniniiD· 1 shared George ChennelliD· 1 shared Graham Mathew FraseriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Diane P. HangerORCID

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2 papers

Recent·Most cited

NeuroscienceAlzheimer s & DementiaPeer-reviewedDec 1, 2025

Proteomic Analysis Links Truncated Tau to Lysosome Motility, Autophagy and Endo-lysosomal Dysfunction

Despoina Goniotaki, Maximilian Hausherr, Steven Lynham…·Deepak P. Srivastava

This study examines how Tau35 protein affects lysosomal function and autophagy, identifying early pathological changes linked to neurotoxicity in tauopathies.

2 citations

mouseproteomics

𝕏 PostBluesky

NeuroscienceAlzheimer s & DementiaPeer-reviewedJul 12, 2024

Tau-mediated synaptic dysfunction is coupled with HCN channelopathy

Despoina Goniotaki, Francesco Tamagnini, Luca Biasetti…·Diane P. Hanger

The paper shows that HCN channel dysfunction is linked to tauopathies, with altered synaptic structure and function in Alzheimer's and Tau35 mouse models.

10 citations

mousehuman

𝕏 PostBluesky