George Chennell

This study investigates the role of ZNF804A in human neurodevelopment, finding it regulates excitatory synapse formation through increased local protein translation in developing cortical glutamatergic neurons.

This paper develops a human neuron-microglia tri-culture platform to study cell-cell interactions during cortical development and disease modeling.

This study examines how Tau35 protein affects lysosomal function and autophagy, identifying early pathological changes linked to neurotoxicity in tauopathies.

This study shows that NLGN3/4X clustering at growth cones promotes neuritogenesis and actin organization in immature human neurons, with ASD-associated variants lacking these effects.

This paper optimizes Airy-beam light sheet microscopy to image 3D structures in hiPSC-derived human cortical spheroids, enabling high-resolution analysis of neurodevelopmental processes.