Author

C. W. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. Leshem· 2 shared A. F. L. Hurlstone· 1 shared A. Hurlstone· 1 shared A. Sassano· 1 shared B. A. Telfer· 1 shared B. F. Kinnear· 1 shared B. Lane· 1 shared C. Evangelou· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

R. Leshem

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance

C. W. Wong, C. Evangelou, K. N. Sefton, R. Leshem, K. Sergiou, M. L. Fernandez Carro, E. Uzuner, H. Mole, B. A. Telfer, D. J. Wilcock, M. P. Smith, K. Kunii, N. R. Perl, P. Lorigan, K. J. Williams, , A. F. L. Hurlstone

This study shows that PARP14 inhibition restores PD-1 checkpoint inhibitor response in IFNγ-resistant tumors by increasing T cell infiltration and reducing regulatory T cells.

Nature Communications · Sep 26, 2023Peer-reviewedCancer Biology

Transitory Schwann Cell Precursor and hybrid states underpin melanoma therapy resistance and metastasis

V. Gopalan, C. W. Wong, R. Leshem, L. Owen, T. Vallius, Y. Shi, Y. Jiang, E. Perez-Guijarro, E. Wu, S. Chin, J. Ebersole, C. Smith, A. Sassano, M. Alves Constantino, M. J. Haley, , K. L. Marie

This paper identifies transitory Schwann Cell Precursor and hybrid states in melanoma that correlate with therapy resistance and metastasis, and shows targeting Hdac2 can sensitize tumors to treatment.

bioRxiv · Oct 14, 2022 · PreprintCancer Biology

Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

L. Han, X. Wei, C. Liu, G. Volpe, Z. Wang, T. Pan, Y. Yuan, Y. Lei, Y. Lai, C. Ward, Y. Yu, M. Wang, Q. Shi, T. Wu, L. Wu, , L. Liu

This study creates a single-cell transcriptome atlas of a non-human primate to explore SARS-CoV-2 targets and immune responses, identifying potential therapeutic targets and mechanisms linking IL6 to viral entry.

bioRxiv · Apr 10, 2020 · PreprintCell Biology

In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics

C. W. Wong, B. F. Kinnear, R. M. Sobota, R. Ramalingam, C. F. Legrand, D. E. Dye, M. Raghunath, B. Lane, D. R. Coombe

This study develops a serum-free culture system using acellular dermal fibroblast-derived matrices to expand keratinocytes while preserving their stem-like properties.

bioRxiv · Aug 7, 2018Cell Biology