Author

B. D. Schweibenz

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

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B. D. Pascal· 1 shared J. Zheng· 1 shared M. Solotchi· 1 shared P. Griffin· 1 shared S. C. Devarkar· 1 shared S. S. Patel· 1 shared

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2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

B. D. Pascal

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1 paper

Recent·Most cited

RIG-I uses its intrinsically disordered CARDs-Helicase linker in RNA proofreading functions

B. D. Schweibenz, S. C. Devarkar, M. Solotchi, J. Zheng, B. D. Pascal, P. Griffin, S. S. Patel

This study identifies a proofreading mechanism in RIG-I that uses the CARDs-Helicase Linker to gate RNA specificity and stabilize interactions, preventing non-specific RNA engagement.

bioRxiv · Sep 23, 2021 · PreprintBiochemistry