Author

B. F. C. Kafsack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:plant (other)· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. Kennedy· 2 shared C. Noetzel· 1 shared C. T. Harris· 1 shared D. Patel· 1 shared D. R. Malave-Ramos· 1 shared K. G. Le Roch· 1 shared L. M. Orchard· 1 shared L. N. Vanheer· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersMicrobiology

K. Kennedy

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6 papers

Recent·Most cited

Safe, effective, and inexpensive clearance of mycoplasma contamination from cultures of apicomplexan parasites with Sparfloxacin.

D. R. Malave-Ramos, K. Kennedy, M. N. Key, Z. Dou, B. F. C. Kafsack

This study identifies Sparfloxacin as a safe, effective, and inexpensive alternative to clear mycoplasma contamination from apicomplexan parasite cultures.

bioRxiv · Aug 30, 2022Microbiology

Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.

R. C. Morillo, C. T. Harris, K. Kennedy, B. F. C. Kafsack

This study adapts CUT&RUN for genome-wide histone modification profiling in Plasmodium falciparum, showing it is more efficient and reproducible than ChIP-seq.

bioRxiv · Aug 1, 2022Microbiology

PfD123 modulates K13-mediated survival and recovery after artemisinin exposure.

C. Noetzel, B. F. C. Kafsack

The paper identifies D123 as a stress-responsive gene contributing to artemisinin resistance in Kelch13-mutant malaria parasites through scRNA-seq analysis and functional experiments.

bioRxiv · Jan 27, 2022 · PreprintMicrobiology

Activity of epigenetic inhibitors against Babesia divergens.

L. N. Vanheer, B. F. C. Kafsack

The paper screens epigenetic inhibitors against Babesia divergens and identifies compounds with potent anti-parasitic activity, highlighting structural and functional differences in inhibitor efficacy between Babesia and Plasmodium parasites.

bioRxiv · Dec 4, 2020 · PreprintMicrobiology

The essential transcriptional regulator HDP1 drives expansion of the inner membrane complex during early sexual differentiation of malaria parasites.

R. Campelo Morillo, X. Tong, W. Xie, S. Abel, L. M. Orchard, W. Daher, D. Patel, W. S. Noble, K. G. Le Roch, B. F. C. Kafsack

This study identifies HDP1 as a transcriptional regulator essential for upregulating inner membrane complex genes during early gametocytogenesis in Plasmodium falciparum.

bioRxiv · Oct 26, 2020 · PreprintMicrobiology

Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages.

L. Vanheer, B. F. C. Kafsack

This study screens 350 epigenetic inhibitors against Plasmodium falciparum asexual and sexual stages, finding 28% of compounds inhibit ≥90% at 10 µM, with a third effective at 1 µM.

Antimicrobial Agents and Chemotherapy · Jun 23, 2020Peer-reviewedMicrobiology