Author

W. S. Noble

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. N. Hoofnagle· 2 shared M. J. MacCoss· 2 shared B. C. Searle· 1 shared B. F. C. Kafsack· 1 shared C. C. Wu· 1 shared D. L. Plubell· 1 shared D. Patel· 1 shared E. D. Parker· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

A. N. Hoofnagle

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Author profile →

3 papers

Recent·Most cited

Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

C. C. Wu, K. A. Tsantilas, J. Park, D. L. Plubell, J. A. Sanders, P. Naicker, I. Govender, S. Buthelezi, S. Stoychev, J. Jordaan, G. E. Merrihew, E. Huang, E. D. Parker, M. Riffle, A. N. Hoofnagle, , M. J. MacCoss

Mag-Net enriches membrane-bound particles from plasma to identify disease-specific proteins, discovering 204 proteins differentiating Alzheimer's disease dementia from controls.

bioRxiv · Jun 10, 2023 · PreprintBiochemistry

The essential transcriptional regulator HDP1 drives expansion of the inner membrane complex during early sexual differentiation of malaria parasites.

R. Campelo Morillo, X. Tong, W. Xie, S. Abel, L. M. Orchard, W. Daher, D. Patel, W. S. Noble, K. G. Le Roch, B. F. C. Kafsack

This study identifies HDP1 as a transcriptional regulator essential for upregulating inner membrane complex genes during early gametocytogenesis in Plasmodium falciparum.

bioRxiv · Oct 26, 2020 · PreprintMicrobiology

Matrix-matched calibration curves for assessing analytical figures of merit in quantitative proteomics

L. K. Pino, B. C. Searle, H.-Y. Yang, A. N. Hoofnagle, W. S. Noble, M. J. MacCoss

The paper demonstrates how to assess quantitative peptide measurements in proteomics using matrix-matched calibration curves and shows that more detected peptides do not guarantee more quantitatively measurable peptides.

bioRxiv · Jul 30, 2019Biochemistry