Author

B. Hwang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. J. Ye· 2 shared A. Marson· 1 shared A. Satpathy· 1 shared B. Yu· 1 shared C. A. Tsuchida· 1 shared C. Chang· 1 shared C. H. June· 1 shared C. R. Hopkins· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

C. J. Ye

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

C. A. Tsuchida, N. Brandes, R. Bueno, M. Trinidad, T. Mazumder, B. Yu, B. Hwang, C. Chang, J. Liu, Y. Sun, C. R. Hopkins, K. R. Parker, Y. Qi, A. Satpathy, E. Stadtmauer, , J. A. Doudna

This study investigates chromosome loss in CRISPR-Cas9-engineered T cells and shows a modified manufacturing process reduces it while preserving editing efficacy.

bioRxiv · Mar 22, 2023Cell Biology

Pooled screening of CAR T cells identifies non-native signaling domains for next- generation immunotherapies

D. B. Goodman, C. S. Azimi, K. Kearns, K. Garakani, J. Garcia, N. Patel, B. Hwang, D. Lee, E. Park, C. J. Ye, A. Marson, J. Bluestone, K. Roybal

This study identifies non-native signaling domains in CAR T cells that enhance proliferation or cytotoxicity, offering improved designs for immunotherapies.

bioRxiv · Jul 11, 2021 · PreprintImmunology