Author

K. Roybal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Marson· 2 shared A. Truong· 1 shared B. Hwang· 1 shared C. J. Ye· 1 shared C. S. Azimi· 1 shared D. B. Goodman· 1 shared D. Goodman· 1 shared D. Lee· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

A. Marson

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2 papers

Recent·Most cited

Pooled screening of CAR T cells identifies non-native signaling domains for next- generation immunotherapies

D. B. Goodman, C. S. Azimi, K. Kearns, K. Garakani, J. Garcia, N. Patel, B. Hwang, D. Lee, E. Park, C. J. Ye, A. Marson, J. Bluestone, K. Roybal

This study identifies non-native signaling domains in CAR T cells that enhance proliferation or cytotoxicity, offering improved designs for immunotherapies.

bioRxiv · Jul 11, 2021 · PreprintImmunology

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

T. L. Roth, P. J. Li, J. Nies, R. Yu, M. L. T. Nguyen, Y. Lee, R. Apathy, A. Truong, J. Hiatt, D. Wu, D. N. Nguyen, D. Goodman, J. A. Bluestone, K. Roybal, E. Shifrut, A. Marson

This paper develops a platform to discover synthetic DNA sequences that enhance T cell functions by integrating them into endogenous genomic sites.

bioRxiv · Apr 12, 2019 · PreprintImmunology