Author

N. Brandes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. J. Ye· 2 shared M. Linial· 2 shared A. Pinedo· 1 shared A. Satpathy· 1 shared B. Hwang· 1 shared B. Yu· 1 shared C. A. Tsuchida· 1 shared C. Chang· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

C. J. Ye

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function

K. Ha, G. B. Loeb, M. Park, M. Gupta, Y. Akiyama, J. Argiris, A. Pinedo, C. H. Park, N. Brandes, F. Ritu, C. J. Ye, J. F. Reiter, M. Delling

This study classifies ADPKD-causing missense variants in polycystin-1 into two categories based on their effects on cell surface localization or ion channel function and suggests small-molecule therapies.

bioRxiv · Dec 4, 2023Cell Biology

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

C. A. Tsuchida, N. Brandes, R. Bueno, M. Trinidad, T. Mazumder, B. Yu, B. Hwang, C. Chang, J. Liu, Y. Sun, C. R. Hopkins, K. R. Parker, Y. Qi, A. Satpathy, E. Stadtmauer, , J. A. Doudna

This study investigates chromosome loss in CRISPR-Cas9-engineered T cells and shows a modified manufacturing process reduces it while preserving editing efficacy.

bioRxiv · Mar 22, 2023Cell Biology

The FABRIC Cancer Portal: A Ranked Catalogue of Gene Selection in Tumors over the Human Coding Genome

G. Kelman, N. Brandes, M. Linial

The FABRIC Cancer Portal ranks gene selection in tumors across 33 cancer types and the human coding genome using genomic and proteomic data.

bioRxiv · Nov 26, 2020Cancer Biology

Substantial Batch Effects in TCGA Exome Sequences Undermine Pan-Cancer Analysis of Germline Variants

R. Rasnic, N. Brandes, O. Zuk, M. Linial

This study identifies substantial batch effects in TCGA exome sequences that affect germline variant analysis across cancer types.

bioRxiv · Oct 16, 2018Cancer Biology