Author

B. J. Altman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Mwangi· 2 shared J. Cazarin· 2 shared A. B. Chan· 1 shared A. L. Hsieh· 1 shared A. M. Knudsen-Clark· 1 shared A. M. Weljie· 1 shared C. Baker· 1 shared C. V. Dang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

D. Mwangi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment

A. M. Knudsen-Clark, D. Mwangi, J. Cazarin, K. Morris, C. Baker, L. M. Hablitz, M. N. McCall, M. Kim, B. J. Altman

This study shows that the tumor microenvironment alters macrophage circadian rhythms, affecting tumorigenesis and macrophage function.

bioRxiv · Feb 14, 2024Immunology

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

J. Cazarin, R. E. DeRollo, S. N. A. B. Ahmad Shahidan, J. B. Burchett, D. Mwangi, S. Krishnaiah, A. L. Hsieh, Z. E. Walton, R. Brooks, S. S. Mello, A. M. Weljie, C. V. Dang, B. J. Altman

This study shows MYC disrupts circadian oscillations in cancer, enhancing biosynthesis and altering metabolism.

bioRxiv · Jan 3, 2023Cancer Biology

Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer

M. Pariollaud, L. H. Ibrahim, E. Irizarry, R. M. Mello, A. B. Chan, B. J. Altman, R. J. Shaw, M. J. Bollong, L. Wiseman, K. A. Lamia

This study shows that chronic circadian disruption increases tumor burden in KRAS-driven lung cancer by enhancing HSF1 signaling and tumorigenesis.

bioRxiv · Jan 31, 2022Cell Biology