Author

C. V. Dang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Gupta· 1 shared A. J. Wolpaw· 1 shared A. L. Hsieh· 1 shared A. M. De Marzo· 1 shared A. M. Weljie· 1 shared A. Maitra· 1 shared A. Rodriguez-Garcia· 1 shared A. Sehgal· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperCancer Biology

A. Gupta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells

D. M. Iascone, X. Zhang, P. Bafford, C. Mesaros, Y. Sela, S. Hofbauer, S. L. Zhang, K. Cook, P. Pivarshev, B. Stanger, S. A. Anderson, C. V. Dang, A. Sehgal

This study shows that metabolic activity in cancer cells affects circadian rhythms, with hypermetabolic states linked to weaker circadian oscillations in both mouse and human tumor cells.

bioRxiv · Nov 8, 2023 · PreprintCancer Biology

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

J. Chen, Q. Zheng, J. L. Hicks, L. Trabzonlu, B. Ozbek, T. Jones, A. Vaghasia, T. C. Larman, R. Wang, M. C. Markowski, S. R. Denmeade, K. J. Pienta, R. H. Hruban, E. S. Antonarakis, A. Gupta, , A. M. De Marzo

The paper develops a method to spatially quantify mitochondrial DNA copy number in cancer tissues and finds increased mtDNAcn in prostate cancer progression, linked to MYC activity.

bioRxiv · Feb 20, 2023Cancer Biology

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

J. Cazarin, R. E. DeRollo, S. N. A. B. Ahmad Shahidan, J. B. Burchett, D. Mwangi, S. Krishnaiah, A. L. Hsieh, Z. E. Walton, R. Brooks, S. S. Mello, A. M. Weljie, C. V. Dang, B. J. Altman

This study shows MYC disrupts circadian oscillations in cancer, enhancing biosynthesis and altering metabolism.

bioRxiv · Jan 3, 2023Cancer Biology

Epigenetic state determines inflammatory sensing in neuroblastoma

A. J. Wolpaw, L. D. Grossmann, M. M. Dong, J. L. Dessau, P. A. Brafford, D. Volgina, A. Rodriguez-Garcia, Y. Uzun, D. J. Powell, K. Tan, M. D. Hogarty, J. M. Maris, C. V. Dang

The paper shows that epigenetic states in neuroblastoma cells determine their response to inflammatory stimuli, with mesenchymal states being more responsive than adrenergic states.

bioRxiv · Jan 27, 2021Cancer Biology

Fatal toxicity of chloroquine or hydroxychloroquine with metformin in mice

N. V. Rajeshkumar, S. Yabuuchi, S. G. Pai, A. Maitra, M. Hidalgo, C. V. Dang

The paper reports that chloroquine or hydroxychloroquine combined with metformin causes lethal toxicity in mice, highlighting potential clinical risks.

bioRxiv · Mar 31, 2020 · PreprintPharmacology & Toxicology