Author

B. J. Manley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. C. Soupir· 2 shared B. L. Fridley· 2 shared J. Chahoud· 2 shared J. Dhillon· 2 shared N. H. Chakiryan· 2 shared O. E. Ospina· 2 shared A. Aydin· 1 shared A. E. Berglund· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. C. Soupir

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

scSpatialSIM: a simulator of spatial single-cell molecular data

A. C. Soupir, J. Wrobel, J. H. Creed, O. E. Ospina, C. M. Wilson, B. J. Manley, L. C. Peres, B. L. Fridley

scSpatialSIM simulates spatial single-cell molecular data to evaluate spatial clustering methods, finding Ripleys K(r) best detects clustering across scenarios.

bioRxiv · Feb 8, 2024Cell Biology

Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment

A. C. Soupir, M. T. Hayes, T. C. Peak, O. E. Ospina, N. H. Chakiryan, A. E. Berglund, P. A. Stewart, J. V. Nguyen, C. M. M. Segura, N. L. Francis, P. M. R. Echevarria, J. Chahoud, R. Li, K. Y. Tsai, J. A. Blasi, , B. J. Manley

The paper uses spatial transcriptomics to identify increased spatial coupling of integrin and collagen IV in immunoresistant clear cell renal cell carcinoma tumors, suggesting integrin as a therapeutic target.

bioRxiv · Nov 16, 2023Cancer Biology

Spatial Clustering of CD68+ Tumor Associated Macrophages with Tumor Cells is Associated with Worse Overall Survival in Metastatic Clear Cell Renal Cell Carcinoma

N. H. Chakiryan, G. Kimmel, Y. Kim, A. Hajiran, A. Aydin, L. Zemp, E. Katende, J. Nguyen, N. Lopez-Blanco, J. Chahoud, P. Spiess, M. Fournier, J. Dhillon, L. Wang, C. Moran-Segura, , B. J. Manley

The paper quantifies cellular density and clustering of immune cells in metastatic ccRCC and finds that CD68+ TAM clustering with tumor cells correlates with worse overall survival.

bioRxiv · Jan 4, 2021Cancer Biology