Author

T. V. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Plant Biology· 2 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

L. E. Jansen· 2 shared S. Peyton· 2 shared A. Addetia· 1 shared A. Carlsbecker· 1 shared A. D. Schwartz· 1 shared A. Haynes· 1 shared A. L. Greninger· 1 shared A. M. Berry· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

L. E. Jansen

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Gene losses resulting in specialized metabolism in the earliest divergent symbiotic Frankia clade can be linked to its low saprotrophic capabilities

F. Berckx, T. V. Nguyen, R. Hilker, D. Wibberg, K. Battenberg, J. Kalinowski, A. M. Berry, K. Pawlowski

The paper investigates nitrogen export in Frankia cluster-2 strains and identifies gene losses linked to specialized metabolism and reduced saprotrophic capabilities.

bioRxiv · May 25, 2022 · PreprintPlant Biology

Longitudinal accumulation of in vivo and in vitro-grown Treponema pallidum subsp. pallidum TprK variants in the presence and absence of immune pressure

M. J. Lin, A. Haynes, A. Addetia, N. A. P. Lieberman, Q. Phung, H. Xie, T. V. Nguyen, B. J. Molini, S. A. Lukehart, L. Giacani, A. L. Greninger

This study shows that T. pallidum generates TprK sequence diversity both under immune pressure and in vitro without immune selection, highlighting the role of gene conversion in antigenic variation.

bioRxiv · Jun 26, 2021Microbiology

Bipartite influence of abscisic acid on xylem differentiation trajectories is dependent on distinct VND transcription factors in Arabidopsis

P. Ramachandran, F. Augstein, S. Mazumdar, T. V. Nguyen, E. A. Minina, C. W. Melnyk, A. Carlsbecker

This study shows that ABA influences xylem differentiation through distinct VND transcription factors in Arabidopsis, revealing genetic independence in cell fate and differentiation rate.

bioRxiv · Sep 28, 2020 · PreprintPlant Biology

Identifying conservation priorities in a defaunated tropical biodiversity hotspot

A. Tilker, J. F. Abrams, A. Nguyen, L. Hoerig, J. Axtner, J. Louvrier, B. M. Rawson, H. A. Q. Nguyen, F. Guegan, T. V. Nguyen, M. Le, R. Sollmann, A. Wilting

The paper identifies conservation priorities in defaunated tropical areas by analyzing species responses to environmental and anthropogenic factors using camera-trapping and environmental DNA.

bioRxiv · Oct 2, 2019Ecology

A Novel Melatonergic Signature Predicts Reccurence Risk and Therapeutic Response in Breast Cancer Patients

M. N. Nguyen, H. Q. Tran, P. L. Luu, V. T. Than, D. Clarke, H. N. Lam, D. T. Nguyen, K. V. T. Le, T. V. Nguyen, M. T. Le, T. X. Hoang, P. Q. Duy, H. T. Tran

The paper identifies an ASMT gene signature that predicts recurrence risk and therapeutic response in breast cancer patients, showing improved outcomes with melatonin and tamoxifen combination therapy.

bioRxiv · Nov 17, 2018Cancer Biology

A Biomaterial Screening Approach to Reveal Microenvironmental Mechanisms of Drug Resistance

A. D. Schwartz, L. E. Barney, L. E. Jansen, T. V. Nguyen, C. L. Hall, A. S. Meyer, S. Peyton

This paper screens drug responses across biomaterial platforms to identify ECM-mediated mechanisms of resistance to RTK-targeted therapies and finds that MEK phosphorylation is a key factor.

bioRxiv · Nov 20, 2017Bioengineering

Zwitterionic hydrogels modulate the foreign body response in a modulus-dependent manner

L. E. Jansen, L. D. Amer, E. Y.-T. Chen, T. V. Nguyen, L. Saleh, T. S. Emrick, W. F. Liu, S. J. Bryant, S. Peyton

This study shows that modulus and zwitterion content independently affect the foreign body response to soft hydrogels, with higher modulus increasing inflammation.

bioRxiv · Sep 28, 2017Bioengineering