Author

B. O. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

I. Beddows· 2 shared B. K. Johnson· 1 shared C. R. Diegel· 1 shared E. A. Boguslawski· 1 shared G. E. Foxa· 1 shared J. Adams· 1 shared K. M. Sorensen· 1 shared K. Melcher· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

I. Beddows

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Generation of a New Frizzled 2 Flox Mouse Model to Clarify Its Role in Development

M. N. Michalski, C. R. Diegel, Z. A. Zhong, K. Suino-Powell, L. Blazer, J. Adams, VAI Vivarium and Transgenics Core, I. Beddows, K. Melcher, S. S. Sidhu, S. Angers, B. O. Williams

The paper generates a new Fzd2 flox mouse model to investigate tissue-specific roles of Fzd2, resolving contradictions in previous global knockout studies.

bioRxiv · Jan 27, 2021 · PreprintCell Biology

Direct therapeutic targeting of SWI/SNF induces epigenetic reprogramming and durable tumor regression in rhabdoid tumor

M. H. Chasse, B. K. Johnson, E. A. Boguslawski, K. M. Sorensen, L. Heo, Z. B. Madaj, I. Beddows, G. E. Foxa, S. M. Kitchen-Goosen, B. O. Williams, T. J. Triche, P. J. Grohar

This paper shows that targeting the SWI/SNF complex with mithramycin and its analogue EC8042 induces epigenetic reprogramming and durable tumor regression in rhabdoid tumors.

bioRxiv · Dec 3, 2019 · PreprintCancer Biology