Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice
J. Lee, K. Wellenstein, A. Rahnavard, A. T. Nelson, M. Holter, B. P. Cummings, V. Yeliseyev, A. Castoldi, C. B. Clish, L. Bry, D. Siegel, B. B. Kahn
This study shows that PAHSAs improve insulin sensitivity in diet-induced obese mice via the gut microbiota, with sex-specific effects observed.
bioRxiv · Sep 28, 2023 · PreprintPhysiology